Wednesday, July 11, 2018

Increasing Energy Consumption to Fuel Asia Circulating Fluid Bed Boilers Industry: Ken Research

Today, energy management is a necessity and is very essential for future. Boilers generate steam which is used to provide space heat, process heat and other variants of heat. Steam boiler is used for generation of heat through heat transfer process from a working fluid or water. The invention of circulating fluid bed boilers has given boilers and power plant operators a greater flexibility in burning wide range of fuels. Circulating fluidized bed operation is a clean process with lower emission pollutants. Key factors affecting the advanced CFB boiler technology are wide fuel flexibility, excellent emission performance and large range of load adjustment. This proved that it is one of the clean coal combustion technologies commercially applied in large scale operations. The need for cost efficient and cleaner combustion technology coupled with stringent environmental regulations in Asia, has led to the development in energy efficient power generation.

According to the study “Asia Circulating Fluid Bed Boilers Industry Situation and Prospects Research Report”, circulating fluidized bed boilers are designed for lignite or coal, from industrial to large-scale utility boilers. Majority of the circulating fluidized bed boilers are designed for fuels such as biomass and various types of waste which are co-fired with regular fuels simultaneously. The industries that are benefitted from circulating fluidized bed technology are textiles, paper, fertilizer, chemicals and petroleum refining. Circulating fluidized bed boilers solve Asia’s energy crisis and decreased dependence on grid power. Decrease in fossil fuels, high degree of carbon emission into the atmosphere, and increasing quantity of hazardous waste from energy production processes are few factors driving the circulating fluidized bed boilers market in Asia.

The various products types available in Asia’s circulating fluidized bed boilers are subcritical, supercritical and ultra-supercritical. Circulating Fluid Bed Boilers in Asian market are utilized in calendering process resin, chemicals, manufacturing and others. Circulating fluid bed boilers market in Asia is spread across China, Japan, India, Korea, Saudi Arabia and other region. The leading players in Asia’s circulating fluid bed boilers industry are Dongfang Boiler Group Co (China), AE&E Nanjing Boiler Co (China), Bharat Heavy Electricals Limited (India), Mitsubishi Heavy Industries (Japan), Shanghai Boiler Works Co (China), Thermax. D Ltd (India) and Doosan Heavy Industries & Construction Company Limited (UAE).

Circulating fluidized bed boilers are used to produce energy from a variety of fuels such as biomass, coal, and peat because they have a very low operating temperature, emit low levels of harmful gases such as carbon dioxide, nitrogen dioxide, and sulphur dioxide. Circulating fluidized bed boilers installation is highest in the oil and gas industry because power consumption has increased rapidly over the past few years. It was observed that there is a significant increase across chemical, manufacturing, and other industries as well. The installed circulating fluidized bed boilers have fuel-flexibility in all the manufacturing industries. China will witness a robust growth in circulating fluidized bed boilers market due to the need for clean fuel and development in power market. Industrialization and infrastructural development in Asian countries such as India and China has witnessed a need for continuous reliable electricity supply which can be provided with the installation of more number of circulating fluidized bed boilers in the next few years.

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Disrupting The Payments Market Via Amazon Pay: Ken Research

According to the study, ‘Alternative Payment Solution: Amazon Pay’, many companies have partnered with Amazon to enable merchants to receive payments. Some of the biggest companies are PayPal, Visa Checkout, Masterpass, Visa, Mastercard, Discover, American Express, Diners Club, and JCB.


The basic benefit behind Amazon is that it simplifies the way sellers accept payments. Users do not have to enter information repeatedly over new purchases such as address or credit card details and thereby streamlining the online purchasing process. All this information is kept secure with Amazon A to Z guarantee that boasts of a glaring security that includes merchant protection and fraud detection. Amazon offers this service to small retailers as well as big enterprises helping them to forge a strong relationship with their customers by improving user experience resulting in less cart abandonment and enhanced loyalty from shoppers. This allows the whole checkout process to be rendered faster thereby improving conversion rates significantly. This enhanced user checkout experience translated into less cart abandonment and enhanced loyalty from users.

Amazon Pay is an Amazon owned online payment processing service which was launched in 2007. Amazon Pay majorly operates in 7 countries namely Germany, U.S.A, Spain, France, Italy, Japan, India and the United Kingdom. The target market that Amazon Pay focuses is the user base of Amazon.com that enables users to pay for their purchases on external merchant websites.

Amazon Pay provides was originally invented with two prime services. These were Amazon Pay and Amazon Pay Express. Users can purchase goods and services using the addresses and payment details such as debit or credit cards stored within the Amazon account. This service is available both via mobile application and website. Amazon Pay Express is a service that is built on Amazon Pay which uses Java to create a button that can be used via any website or Wordpress plug in. The uniqueness of this service comes from the fact that it does not require full E commerce integration.

In 2018, Amazon announced the launch of in skill purchasing to all Alexa developers, along with Amazon Pay for skills. Developers can generate revenue from voice applications on Alexa-powered devices like Amazon’s Echo speakers. For instance app developers can charge for voice based games or offer other content and simultaneously receive payment via Amazon Pay for their applications.
Amazon introduced a new feature called Amazon Pay Places which allow users to order ahead shopping or pay for in store purchases using their Amazon App. Instead of using cash, check, credit or debit while shopping out in the real world, customers can just use thier Amazon account information. The implementation of Pay Places involves a partnership with the TGI Friday’s restaurant chain which is set to expand to other physical and retail stores.

With the introduction of Amazon Pay, Amazon is expected to disrupt the global payments market. Amazon pay reaps benefits to consumers of greater ease. Since, consumers today prefer to make use of technology that is more convenient than its predecessors; Amazon Pay can easily improve its presence due to its unique feature.

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Science Behind Osteomyelitis And Its Prevention Market Outlook: Ken Research


According to the study OSTEOMYELITIS GLOBAL CLINICAL TRIALS REVIEW, H1, 2018, this infection is usually treated with antibiotics given into veins or through surgery.
Osteomyelitis is an infection of a bone caused by bacteria, mostly Staphylococcus aureus. It is pretty rare and certain chronic conditions like diabetes tend to increase the risk of osteomyelitis. It results in pain and redness around the affected region apart from symptoms like fever, nausea and chills. The disease can easily be diagnosed by X-ray, CT scan and blood tests. There are currently many advances being made in surgical treatment and medicine which are incorporating technology and research. The result of these advances in surgical treatment and antibiotic therapy is opening doors for various treatment options of osteomyelitis. The barriers to proper treatment are being studied in order to better understand the ways to intrude them. This can be proven by the developments that have taken place in osteomyelitis treatment such as the study carried out by research teams. An Institut Pasteur-CNRS research team has characterized a Staphylococcus aureus gene involved in virulence, bio film formation and resistance to certain antibiotics.
Since osteomyelitis is mainly an infection, it can easily flourish around open wounds and recently treated areas around bones. New technologies for the prevention of healthcare associated infections are increasingly being developed and marketed to healthcare centers worldwide. This comes due to the realization of the fact that while there is substantial promise in simulated test environments, decreasing infections in the clinical setting has not been well established. There are a number of factors that raise concern in this respect, the most common ones being cross transmission in the hospital environment arising from contamination of hospital surfaces, contamination of medical devices and hands or clothes of medical personnel. Studies too show the alarming situation as more than one-third of hospital acquired infections are caused by contamination of medical workers’ hands. A patient admitted to a hospital room in which the previous occupant had methicillin-resistant Staphylococcus aureus has a significantly increased risk of acquiring the pathogens.
In response to the crippling situation, there have been a number of developments like the use of Adenosine triphosphate (ATP) levels and fluorescent markers to monitor the microbial contamination levels. Manual cleaning remains an important precursor step as gross organic soil must be removed from surfaces to allow penetration of germicidal vapour/aerosol or radiation emitted from hydrogen peroxide or UV light emitting devices. Several antimicrobial coatings are under pre-clinical study for their potential application to surfaces in healthcare centers. However, Coatings copper has been studied most extensively.
Antibiotics are increasingly undergoing research to increase their effectiveness. Many pharmaceutical companies are incorporating existing knowledge and expertise in their experiments in an order to expand their scope. Osteomyelitis among other ailments is providing opportunities to the pharmaceutical research sector to tackle microbial attacks. There is growing awareness about prevention of accelerating factors like hygiene and technologies like hand hygiene monitoring systems and antimicrobial textiles among others are said to help change the scenario.       
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Bone Cell Therapy To Treat Osteonecrosis Market Outlook: Ken Research


Many leading orthopedic companies are researching bone cell therapies and are trying to open up possibilities of incorporating stem cells in this regard. According to the study ‘Osteonecrosis Global Clinical Trials Review, H1, 2018, Bone Therapeutics is a leading cell therapy company addressing high unmet needs in orthopedics and bone diseases. The Belgium based company operates a diversified portfolio of bone cell therapy products in clinical development across a number of disease areas targeting markets with large unmet medical needs and limited innovation.

Avascular necrosis also called osteonecrosis or bone infarction is the death of bone tissue caused by interruption of blood supply. It is a focal infarct of bone that may be caused by specific etiologic factors or may even be of idiopathic nature, meaning it can arise out of unknown reasons spontaneously. It may lead to pain, limitation in motion, joint collapse and osteoarthritis. Diagnosis is done by X-ray and MRI with the latter being more sensitive and specific. In early stages, surgical procedures may slow or prevent progression. In later stages, joint replacement may be required for relief of pain and maintenance of function. It is often suspected in patients with unexplained non-traumatic pain in the hip, knee or shoulder.

Osteonecrosis is most often a complication of displaced hip fracture but factors that compromise bone blood flow such as chronic corticosteroid use and excessive alcohol consumption tend to increase risk of non-traumatic osteonecrosis. The hip (femoral head) is most commonly affected followed by the knee and shoulder. The wrist and ankle are less often involved. Since osteonecrosis affects mostly the joints and bones, the most widely used treatment is via surgery carried out by orthopedic surgeons. Core decompression and bone grafting are popular in this respect. Various surgical procedures are helpful to relieve pain and improve function of the affected femoral head in the early stages; however, the secondary trauma caused by surgical intervention remains an inevitable clinical problem where surgical procedures are unable to prevent deformity and collapse in deteriorating cases of osteonecrosis of femoral head.

Currently the attention of researchers is focused on three key points that will help maximize the efficiency of existing resources. The first, enhancing the sensibility and accuracy of diagnosis to raise the rate of early diagnosis, the second, improving surgical operation technology or developing minimally invasive surgery to avoid the secondary trauma caused by surgical intervention and the third, exploring drugs or grafting products to promote reparative bone remodeling thereby obtaining a good prognosis. Following advances in basic science, many new insights focus on bone tissue engineering to optimize therapies and facilitate prognosis of osteonecrosis.

Research is also attempting to answer the question on how to reverse the early stage of osteonecrosis and promote reparative bone remodeling as the key for maintaining the undestroyed joint adjacent to lesion areas and making available therapies to facilitate a good prognosis. In this review, disease classifications, current treatment options, potential therapies and the relevant translational barriers are being reviewed in the context of clinical application and preclinical exploration, which would provide guidance for preferable treatment options and translation into novel therapies.

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Industrialization to Fuel Asia Cold Rolling Flat Steel Industry in the Future: Ken Research

Asian iron and steel industries are the backbone of the economy portraying the performance and development of the countries. Iron and steel are extensively used and are recyclable materials available on Earth. It was observed that GDP growth of any economy significantly depends upon the industrialization, Therefore, rapid industrialization in development of Asian economies such as India and China is likely to witness a demand for iron and steel products. Rapid urbanization, rising level of disposable income in emerging economies, and growing population are projected to be the major market drivers for cold rolling flat steel industry. It was estimated that there is a huge investment in infrastructure which will continue over the next few years with a positive impact on the cold rolling flat steel industry.

Cold rolled steel is basically hot rolled steel that is further processed in cold reduction mills. The hot rolled steel is cooled at room temperature followed by annealing and tempers rolling which produces steel with closer dimensional tolerances. Cold rolled steel is used in the manufacture of all steel products; however, the products manufactured refer to the rolling of flat rolled sheet and coil products. Cold rolled steel is produced in bars and usually referred to as cold finishing because it undergoes cold drawing and/or turning, grinding and polishing. This procedure results in higher yield, high tensile strength, avoids costly thermal treatments, gets rid of surface imperfections, narrows the original size tolerance range and improves surface finish. All cold rolled steel products provide a superior surface finish, superior in tolerance, concentricity, and straightness compared to hot rolled steels. It is hard to work on cold rolled steel bars due to the low carbon content and it is typically annealed, making it softer than hot rolled sheet. The corrosion in a cold-rolled steel sheet surface requires an aqueous electrolyte to get in contact with that surface. Cold-rolled steel is free from corrosion at relative 100% humidity, steel surface is free of contaminants, surrounding atmosphere is uncontaminated, and condensation is avoided by keeping the temperature constant.

According to the study “Asia Cold Rolling Flat Steel Industry Situation and Prospects Research Report”, the price of iron ore in Asia is very volatile in nature due to its huge demand. Cold-rolled flat steel products are supplied through direct supply agreements or third-party supply agreements. Majority of the manufacturers in Asia adopt the forward integration technique which enables them to sell their products directly to customers. Cold-rolled flat steel product companies such as Tata Steel Limited and Essar have their own distribution channels. Emerging economies such as China, India, and Japan are expected to witness high consumption of cold-rolled flat steel products due to rising population, demand for durable and quality products. China accounts for a largest share in Asia’s cold-rolled flat steel products market and will continue over the next few years. Cold-rolled flat steel industry is highly competitive due to more number of multinational manufacturers. The leading players in cold rolling flat steel in Asian market are Ansteel Group, Baosteel Group, JFE, Gerdau, Evraz Group, Hebei Steel Group, CSC, Arcelormittal, Essar Steel, POSCO, United States Steel Corporation, Thyssenkrupp AG, Voestalpine Group, Steel Authority of India Limited and SSAB. Cold rolling flat steel in Asia market is categorized based on product types such as low carbon steel, medium carbon steel and high carbon steel.

Cold-rolled flat steel sheets and strips accounted for the largest market share in Asian markets. Variants of steel are used in the manufacture of different types of materials such as carbon, alloy, stainless and tool depending on the applications. Cold-rolled flat steel products are used in industrial applications, architecture, and transport industries on account of its benefits such as corrosion resistant, good adhesive properties, welding properties, light-weight and strong. Cold rolled flat sheets are best suitable for manufacture of electrical appliances, automobiles, and other commercial applications such as chain parts, automotive AT parts, automotive clutch parts, sprocket gears and automotive seat belt parts. Cold-rolled flat steel plates are thick and are produced on either discrete plate mill or a coiled plate mill. The plates are made based on various applications such as low-alloy, heat-treated and high strength which are used for logging equipment and mining equipment. Cold-rolled flat steel plates are also used in construction of bridges, buildings, ship building, offshore structure, hydro power station, storage tanks, boilers, pressure vessels and machinery owning to properties such as high tensile strength, atmospheric corrosion resistant, seawater resistant and abrasion resistant.

There is a huge demand for cold-rolled flat steel products in various industries and the trend is expected to continue due to its advantages compared to other materials such as resistance to shock, corrosion, cost efficiency, environment friendly and safety. The major industries utilizing cold-rolled flat steel in Asia are the automotive and the construction sectors. This trend will drive the utilization of cold-rolled flat steel products. The use of cold-rolled flat steel in automobiles has led the manufacturers to achieve anticipated standards of strength and protection for vehicles at comparatively low costs. However, increasing focus towards fuel efficiency and weight reduction of automobiles is expected to hinder the growth of Asia’s cold-rolled flat steel market in automotive application over the next few years.

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Rechargeable Batteries Market to Drive Asia Cobalt Products Industry: Ken Research

Cobalt is demanded in excess for various manufacturing process and therefore, it is often referred to as blue gold. The price of cobalt increases almost every year due to the metal’s importance in the lithium battery industry and its limited supply. It was estimated that the demand would increase drastically when the electric car market booms and lithium batteries will start powering the world. Over 60% of global supply of cobalt is produced in Congo with huge cobalt reserves. The other cobalt mining nations around the globe are China, Canada, Russia, USA and Australia. Cobalt is mostly mined as a bi-product of nickel and copper production. The available lithium batteries are fuelling the needs of the ever growing global population. Lithium battery is a chemical stew of lithium metal oxides such as phosphate, iron, manganese, spodumene, aluminium, tantalite, titanium, cobalt and lithium. Germany's BMW car manufacturers, and electronic gadget makers, such as Apple, are hunting for cobalt supplies around the world. A multinational competition was observed in the cobalt market due to a tough challenge for many products that are based on rechargeable batteries. Instead of finding fresh supply of cobalt reserves, researchers are also keen to find a metal to replace cobalt in batteries. This situation may also lead to delay or even halting the new generation electric vehicles.
According to the study “Asia Cobalt Products Industry Situation and Prospects Research report”, cobalt consumption in non-metallurgical applications has witnesses more consumption than in metallurgical industries in past few years. There is a huge demand for Li-ion batteries in advanced technological applications and electric vehicles which is driving the cobalt market. These applications need raw cobalt in chemical form, such as cobalt sulphate with high purity standards. Cobalt sulphate is used by pre-cursor manufacturers, cathode compound producers and integrated battery manufacturers. Most of the Asian Li-ion battery manufacturing units are located in China, South Korea, Japan and Taiwan. The major consumers of cobalt in Asian industries are manufacturers of electric vehicles and battery industry.
Cobalt products are used in various industries such as aerospace, automotive, electronics, medical domain and other sectors. It is used in manufacturing everything from alloys for jet engines, gas turbines, drill bits, magnets, orthopaedic implants and many more products. Cobalt Products market is categorized into independent mineral, commingling and other. Various cobalt product types are sintering of cobalt, cobalt alloy and cobalt salt. The major users of cobalt products are battery materials, calendaring process resin, super heat resistant alloy, tool steel, hard alloy and magnetic materials. Around 75% of lithium batteries use cobalt in the manufacturing process.  It was observed that lithium batteries include cobalt as a chief component mineral in their cathodes. Geographically, Asia cobalt products market is spread across China, Japan, India, Korea, Saudi Arabia and other regions. The leading players in global cobalt products market are Vale (BR), Sherritt International (CA), Glencore International AG (Switzerland), ENRC(Switzerland), Freeport-McMoRan Copper & Gold Inc.(US), Grammy(CN), China Metallurgical(CN), Shandong Jinling Mining Co., Ltd(CN), Yunnan Copper Group(CN), Jinchuan Group Co., LTD(CN), Zhejiang Huayou Cobalt Industry Co. LTD(CN), Jiangsu Kalik Co. LTD(CN), Zhejiang Jialike Cobalt Nickel Material Co. LTD(CN), and Nanjing Cold Cobalt Industry Co. LTD(CN).
Tesla Motors is a leading company in the electric automotive industry, which originally used battery cathodes comprising lithium, nickel, aluminium, and cobalt, but the new battery revealed consists of nickel, manganese, and cobalt. By the year 2022, Toyota will start production of its cobalt pyrophosphate cathodes for automobile use. However, smartphone batteries account for a major share in Asia’s market for cobalt.
The continuing fluctuations in oil prices and the demand for environmentally-friendly alternatives to conserve fossil fuels are the major factors that are driving the growth in batteries for energy generation. Batteries power electric vehicles and essential everyday electronic devices such as smartphones ¬which are fuelled by lithium ions along with a raft of other metals including the relatively unknown cobalt. The increasing demand for cobalt in the manufacture of rechargeable batteries will drive Asia’s cobalt products industry over the next few years.
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Neos Revolutionizing Business Ecosystem: Ken Research


According to the study, ‘FINTECH PROFILE: NEOS’ The key partners of NEOS are Aviva Ventures, Munich Re, Hiscox, Zoopla Property Group, Eos Venture Partners. In 2016, NEOS partnered with Collibra, an international player in data governance technology. This partnership will allow for collaborative data governance that helps to integrate business with information technology. Via this collaboration, clients can expect faster data management maturity enhancements, fewer data issues and a lower risk exposure.
NEOS is lead by industry specialists, Earnst Renner, Managing partner, Rob Nocera, Partner Carla Gregory, Senior Principal and Eric Truntz, Senior Principal
NEOS offers unique data management and consultancy services that have the potential to enhance various business verticals. With ever changing technological ecosystem, companies like NEOS have the potential to grow and expand their operations are various regions both small and large.
NEOS, a financial technology company was established in 2000 providing proactive business solutions to leading Insurance, Financial Services and Information Services companies with prime operation in North America, Europe and Asia – Pacific. NEOS helps to realize full potential of any business by craftily integrating technology within everyday business requirements. NEOS focuses on designs and delivers new strategies and solutions to help businesses to overcome operational, regulatory, and technological challenges.
NEOS offers many signature solutions. These include FutureWeek process redesign, Business Processing outsourcing flex, program value assurance, Futurefirst product score card, Data leak accelerator and Data governance accelerator. Program value assurance is an 8-10 week method to carefully analyze business initiatives to ensure successful deployment. The business analysis works in a logical sequence. NEOS helps to identify key issues and shortcoming relating to finances followed by connecting organizational vision with the final outcome of the initiative and verifying its relevance using simple metrics. The process further ensures that no amount is wasted on any technology or action that does not lead to value addition by conducting comprehensive audits. Employees are much needed for any organizational success. The willingness to adapt to new initiatives is where major problem lies. NEOS helps employees to adapt to changes and perceive the change with an open mind. The final step is to ensure effective communication amongst all stakeholders. Any miscommunication can lead to high risk of failure. NEOS takes over the communication of relevant and precise information to all whom it is intended for.
The major operational zone for NEOS is Insurance Industry. It provides life insurance, pension and retirement, employee benefits, property and casualty and annuity oriented technology and financial services. Their technology modernization service focuses on creating a fast paced dynamic and holistic technological environment where concepts like outdated are themselves outdated.
Recently, NEOS launched Internet of Things powered home insurance in United Kingdom. The home insurance product focuses on sensor technology and wireless connectivity to diminish home risks for instance fir, water damage, burglary. The customers are required to install a third party internet connected sensors that trigger in case of any calamity or issue and sends data to the user and insurance companies. The users can manage various components of the sensors and can control some components for instance motion sensors and smoke detectors via their application.
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Kuwait Warehousing Market is Driven by Rise in Imports for Food and Beverage Sector Coupled with Expansion of Warehouse Capacity: Ken Research



The warehousing market of Kuwait has witnessed surge in imports and exports activity majorly due to increase in demand of food and beverage industry, chemical, electronics, pharmaceuticals and other industries. Since Kuwait is highly dependent on imports for frozen food, dairy products, consumer staples, pharmaceuticals and polymers, which has increased the need of warehouses among end users. The companies owning warehouses have also attributed to the growth of the industry such as DHL with 1 warehouse, Dolphin with 2 warehouses and UAGSCO with 4 warehouses in Kuwait.

Over the past few years, rapid retail market developments have been evident in Kuwait with a continuous increase in organized retail or modern shopping across the country. Additionally, the growing trend of online shopping in Kuwait has led to establishment of new fulfilment centers for E-commerce companies to store their goods.

In Kuwait, majority of the cold storage warehouses are located near to sea ports such as Shuwaikh Port, Shuaiba Port and Doha Port. However, with the expansion of companies operating in warehousing market, growth is observed in construction of setting up of new warehouses regionally. Major regions where new warehouses have been set up are Ardia, Mina Abdullah, Ahamadi, Amghara, which are generally used for keeping industrial goods as these regions are close to industrial area.

Majority of the international logistic companies operating in Kuwait does not have their personal warehouse and they generally operate on the basis of asset light model in which they rent a warehouse for few number of days and perform their logistic services rather than setting up their personal warehouse in various countries, this has positively inclined the demand for warehouses in the country. Warehousing players should focus on increased cargo handling or industrial freight warehousing along with the development in other towns apart from Al Jahra Governorate.

Products Covered:
Kuwait Logistics and Warehousing Market by Business Model (Industrial Freight/Retail, Container Freight, Cold storage, Agriculture and others) by End User (Food and Beverage, Chemicals, Electronics, Pharmaceutical, E-Commerce, Consumer Durables and Others)

Companies Covered:
Agility Kuwait, KGL Logistics, Dolphin Logistics and DHL Kuwait

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Menopausal Disorders Drug Development Research Report : Ken Research


Menopausal Disorders Drug Development Research Report provides an overview of the pipeline landscape for menopausal disorders. It provides comprehensive information on the therapeutics under development and key players involved in therapeutic development for postmenopausal osteoporosis, vaginal atrophy and vasomotor symptoms of menopause, and features dormant and discontinued products.
Postmenopausal osteoporosis is the most common form of osteoporosis. It affects many women after menopause. Symptoms include back pain, loss of height, or spinal deformities such as stooped posture. Risk factors include age, gender, family history, bone structure and body weight. There are 20 products in development for this indication.
Vaginal atrophy is thinning, drying and inflammation of the vaginal walls due to the body having less estrogen. Signs and symptoms include vaginal dryness, vaginal discharge, genital itching, burning with urination, and urgency with urination, urinary tract infections and urinary incontinence.
Risk factor includes smoking. Smoking impairs blood circulation, depriving the vagina and other tissues of oxygen. Tissue thinning occurs where blood flow is decreased or restricted. There are five products in development for this indication.
Vasomotor symptoms of menopause include hot flashes or night sweats that result from sudden opening of the blood vessels close to the skin, usually due to hormonal fluctuations in menopause and perimenopause. These symptoms are caused due to some medications, estrogen withdrawal, thyroid disease, diabetes, hyperhidrosis, anxiety and panic disorders, obesity, hormonally active tumors, chronic infections and neurological disorders. There are 12 products in development for this indication.
Molecular targets acted on by products in development for menopausal disorders include tumor necrosis factor ligand superfamily member 11, parathyroid hormone receptor and progesterone receptor. Companies operating in this pipeline space include Amgen, TherapeuticsMD and Ipsen.
The report also includes the following details:-
- Which companies are the most active within each pipeline?
- Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
- To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
- What are the most important R&D milestones and data publications to have happened in this disease area?
- Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
- Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication and a comprehensive picture of recent updates and milestones for each
- Analyze the companies, institutions and universities currently operating in the pipeline and the products being fielded by each of these
- Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration
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