Thursday, September 27, 2018

Primary Immune Deficiency Market Research Report: Ken Research


According to study, “Primary Immune Deficiency (PID) - Pipeline Review, H2 2018” some of the major players that are working in the primary immune deficiency are Biotest AG, Cellective Bio TherapyInc, ADMA Biologics Inc, Casebia Therapeutics, Genethon SA, GC Pharma, GigaGenIncm, Novartis AG, Leadiant Biosciences Inc, Octa pharma AG, Sangamo Therapeutics Inc, ProMetic Life Sciences Inc, Shire Plc, Therapure BiopharmaInc, Taiga Biotechnologies Inc, UCB SA, X4 Pharmaceuticals Inc.

Primary immunodeficiency (PTD) is a large group of disorders in which part of the body's immune system is missing or does not function normally. It allows infections and other health problems to occur more easily. Some forms of PID are usually hereditary while some disorders are not recognized until adulthood. There are many signs and symptoms of deficiency such as blood disorders, digestive problems, delayed growth & development, autoimmune disorders, frequent & recurrent pneumonia, ear& skin infection and inflammation & infection of internal organs etc.

PIDs are classifies into many categories according to the component of the immune system such as T cell deficiencies, B cell deficiency, combination B & T cell deficiency, complement deficiencies and idiopathic growth hormone deficiency etc. T cell deficiency is caused by decreased function of individual T cell. T cell’s normal function is to help with the human body’s immunity. B cell deficiency is caused by a lack of infection-fighting producing B cells or immunoglobulin that is not functioning properly. Combined B-cell and T-cell immunodeficiency is a group of medical disorders that are the result of genetic defects in cellular and humoral immunity, also called severe combined immunodeficiency.

There are many complications are involved in PID such as recurrent infections, autoimmune disorders, damage to (heart, lungs, nervous system or digestive tract), slowed growth, increased risk of cancer and death from serious infection. There are many drug profiles are involved in primary immune deficiency, which are; BT-595, aldesleukin, cell therapyfor RAG deficient, cellular immunotherapy, gene therapy for x-linked SCID, elapegademase, gene therapy to activate IL2RG for x-linked SCID, hyaluronidase & immune globulin, OTL-101, RI-002, RPL-201, seletalisib, stem cell therapy to activate IL2RG for SCID-X1, TBX-1400, strimvelis and X-4P001.

BIVIGAM is an intravenous immune globulin indicated for the treatment of primary humeral immunodeficiency. It includes agammaglobulinemia, Wiskott-Aldrich syndrome and severe combined immunodeficiency. BIVIGAM is a purified, sterile, ready-to-use preparation of concentrated polyclonal immunoglobulin antibodies. Antibodies are proteins in the human immune system that work to defend against infections and disease. In June 2018, ADMA optimized the production process for BIVIGAM and submitted a prior approval supplement to the United States food & drug administration to amend the biologics license application with a target action under the prescription drug user fee act. If prior approval supplement is approved by the food & drug administration. The immunodeficiency can be subtle and vary in presentation which involves recurrent or unusual infections, malignancies or autoimmune phenomena.Primary care providers assess and treat PID's patients a clinical immunologist can advise on further diagnostic tests and management of patients. Collaborative patient care among health care providers can save patient lives and improve long-term outcomes.

At present, there is no single assay that identifies all forms of PID. Therefore need a challenge of current newborn screening paradigms andit is estimated that PID will involve up-front next generation sequencing.

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Bahrain Plastic Pipes and Fittings Market is Driven by Increasing Private Investment in Infrastructure and Development Projects and Increase of Government Focus on Non-Oil Sectors of the Economy: Ken Research

Programmes and policies to promote tourism increase in residential construction projects to meet excess housing demand and changes in consumer preference towards high quality plastic pipes for their desirable properties have driven the growth of plastic pipes and fittings in Bahrain.
The Bahrain Plastic Pipes and Fittings Market is at its late growth stage. The market growth has stagnated as the decrease in oil prices has impacted the demand of plastic pipes and fittings in the country and there were not many infrastructure projects coming up in the recent years. The industry is highly correlated with the development in the infrastructural, mining and construction of new house dwellings in the country. There has been a trend of substituting PVC pipes and fittings by PE pipes and fittings in the past few years due to changes in consumer preferences. The water supply and sewage end use application continues to be the leading end user application of the plastic pipes and fittings in Bahrain. The market is concentrated with few organized players dominating the market.
The organized sector dominates the market due to its superior product quality and low cost. Government schemes such as Government Action Plan (GAP) of FY’15- FY’18 to construct more housing units, allowing 100% foreign ownership in additional sectors to support FDI growth and schemes to promote tourism in the country have contributed majorly to the market as these schemes have quadrupled the demand for plastic pipes and fittings in the country. There has also been a shift in consumer preference from steel pipes to UPVC and HPDE pipes in water supply systems as they can withstand the pressure along with being significantly economical. Plastic Pipes and Fittings Market in Bahrain is highly competitive amongst the major players, and consequently, companies are increasingly focusing on product diversification to consolidate and expand their market shares.
Analysts at Ken Research in their latest publication “Bahrain Plastic Pipes and Fittings Market Projections to 2022- By Type of Pipes (UPVC, CPVC, PE and Others) and Type of End Use Applications (Irrigation, Water Supply and Sewage, Plumbing, Chemical and Oil and Others)” believe that reduction of wastage and spillage while manufacturing, keeping up with advanced technology, tracking upcoming government and private construction projects, diversification of product line, supply of plastic resin from multiple sources, increasing production capacity of PE products, usage of by-product and focus on increasing manufacturing capacity for fittings will aid the manufacturers of plastic pipes and fittings in Bahrain to grow and achieve higher profits.
Key Segments Covered
By Type of Pipe
uPVC, PVC and CPVC, PE, PPR, ABS, PVDF and others
By Type of Market Structure
Organized Market
Unorganized Market
By Type of End User Application
Water Supply and Sewage, Plumbing, Chemical and Oil, Irrigation, Gas Transmission, Cable Protection, Healthcare and Automotive Industries and others
Key Target Audience
Plastic Pipes and Fittings Manufacturers, Plastic Resins Manufacturers, Major Importers of Plastic Pipes and Fittings, Private Equity Ventures
Time Period Captured in the Report:
2012-2017 – Historical Period
2017-2022 – Future Forecast
Plastic Pipes and Fittings Manufacturing Companies:
Bahrain Pipes, Gulf Plastic Industries, Tylos Plastic Industries, Bahrain National Plastic Company
Key Topics Covered in the Report
Raw Materials for Plastic Pipes Bahrain
Plastic Pipes and Fittings Manufacturing Bahrain
HDPE Pipes Industry Bahrain
Plastic Pipes Manufacturers Bahrain
Bahrain Water Projects
By-Products of Plastic Pipes
Plastic Pipes Applications Bahrain
Plastic pipes manufacturing Bahrain
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Renewable Energy Development to Remain Focus in Spain Power Sector: Ken Research


According to study, “Spain Power Market Outlook to 2030, Update 2018 - Market Trends, Regulations, and Competitive Landscape” some of the major companies that are currently working in the Spain’s power market are Union fenosa, Acciona, ACS group, EMTE, Naturgy, Iberdrola, Torresol energy, EDP renovavels, Bio fuel systems.

Spain is the largest power market in southwestern Europe. It is moving towards the sustainable development of power sector. The power sector in Spain was privatized in 1985. About 33.7% of the power generated in the country came from renewable energy sources. By the end of 2017, the Spain had installed power generation capacity of 104,122 megawatts (MW).

New methods of energy production and development are being developed. Major method of energy production is the use of renewable resources such as wind energy. Spain is dependent on imported oil due to its geographical position and lack of natural resources. In order to reduce this dependence, government aims to shift towards renewables by promoting wind energy. By the end of 2017, the Spain had installed windpower generation capacity of 23,121MW.

In Spain, another renewable resource is hydro energy. Spain is extensively utilizing its hydropower potential in order to ensure safer environment for its future generation. Country has numerous hydropower projects that are still under construction and some that began operations long back. In 2017, the Spain had installed hydro power generation capacity of 20,354MW. One of the advantages of this source of power is that it is cheaper, expands irrigation and provides water& 19% of electricity.

In Spain, wholesale electricity market is operated by OMIE. OMIE is the daily market and its purpose is to handle electricity transactions for the following day through the presentation of electricity sale and purchase bids by market participants.
In Spain, the private sector companies are investing in smart grid development and R&D to promote increased competitiveness for Spanish utility providers. It is estimated that a 1€ investment in smart grid technology generates 2 EUR - 2.3 EUR in economic benefits. The stakeholders in the energy sector in the evolution of Spain’s smart cities include government entities at the national level such as the Ecological Transition Ministry, the National Commission on Markets and Competition, Red Electrica de Espana, the Institute for Diversification and Energy Saving and OMIE that manages the entirety of the markets.

In 2017, Spain is the fifth country in the world in terms of installed wind power after China, the US, Germany and India. The future of power industry is expected to be bright especially due to the strong support that the Spanish regulatory framework provides. In the upcoming years there will be an extreme investment, change in government’s policies in favor of these resources and auctions are expected to promote electricity generation from renewable. Opportunities exist for the transmission system to connect the remote areas. The transmission systems are expected to ensure supply/demand balance. Electricity delivery and demand side management solutions as are expected to increase due to smart grid deployments. Spain has also leveraged its development by pledging to meet between 30-44% of gross final energy demand through clean energy by 2030, and by 2020, country has pledged to meet 20 percent of the gross final energy demand through clean energy.

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Key Projects Of Oil And Gas In The Sub-Saharan Africa Market Outlook: Ken Research


With the increasing projects related to oil and gas production and current scenario represents the significant growth of the oil and gas production in the Sub-Saharan Africa. In a research it is observed that the oil and gas industry in Africa pursues to manifest considerable growth, with new hydrocarbon provinces advancing at an important step. According to the report analysis, ‘H1 2018 PRODUCTION AND CAPITAL EXPENDITURE OUTLOOK FOR KEY PLANNED UPSTREAM PROJECTS IN SUB-SAHARAN AFRICA – NIGERIA AND MOZAMBIQUE DOMINATE CAPEX OUTLOOK states that Nigeria escort with the highest number of planned projects, followed by Mozambique and Ghana. Moreover, the main oppositions can be identified by the institutions in the oil and gas industry have remained strongly unchanged with the top three problems of undetermined regulatory structure, poor physical infrastructure and corruption also detected as the huge challenges in the recent past years. Furthermore, the various organizations were worked accordingly for facing these challenges and Nigeria was one of the few countries where defendant did not appraise it to be of the top-three issues or challenges to advancing the market.
By 2025, in Sub-Saharan Africa, a total of 64 key crude oil and natural gas projects are predicted to start operations whereas, key projects in Sub-Saharan Africa are anticipated to grant up to 2 mmbd to global crude production and more than 8 bcfd to the global production of gas in 2025. In addition, the taxation concern has also become an important issue to the companies of Africa as uncertain taxation as well as a latest tax regulation has made a supplementary financial burden for key players. Besides this the Africa is observing the advancement of one of the more crude oil projects in the recent trend. Furthermore, there are numerous projects around the globe that are integrating latest technologies in order to continue the relevant projects are being developed in Africa. These projects of crude oils are a revolutionary step in the oil and gas industry and are expected to open a wide number of employments during the implementations of projects. From the main operators, Eni East Africa SpA, Total Upstream Nigeria Ltd, and Esso Exploration and Production Nigeria Limited steering in terms of operatorship of planned and broadcast projects.
By the time numerous development have been taken place in Africa that are supporting crude and natural gas projects and these advancements are being brought related for the dealing purposes. This evidently signifies the Africa’s potential in the oil and gas production mechanism in 2025. Moreover, the government and national oil key leading players playing a n efficient role in significant growth and advancement in Sub-Saharan Africa’s oil and gas sector and many regions have a host of strict rule and regulations that build challenges for key players and investors to overcome across the globe. Furthermore, with the good governance and realistic schedule in the Sub-Saharan Africa are deemed to be essential for improved efficiencies and cost management. Therefore, in the coming years it is expected that the production of oil and gas in the Sub-Saharan Africa will grow with the more projects in this region over the decades.
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Thailand Freight Forwarding Market is expected to reach around THB 1.4 Trillion by the year ending 2022: Ken Research

·         The military government in Thailand aims to position the country as the gateway to ASEAN and in order to do so it has announced its will to support the logistics sector by strengthening the infrastructure and implementing trade friendly policies.

·         Road is by far the most popular medium for moving freight within the country and will continue to grow owing to integration of regional economies.

Thailand has signed multiple free trade agreements (FTAs) with large economies like China, USA, India and others. The country as a WTO member since 1995 has been open to foreign firms operating and manufacturing from the Thailand thus helping it to have a trade surplus over the years. Thailand’s agreements with the ASEAN community have led to an increase in cross-border freight transportation via roadways and ports without any major limitations. Some of the major export products include textiles and footwear; fishery products, rubber, jewellery, cars, computers, electrical appliances and others. Thailand’s central region is one of the ideal locations for Thailand’s exports and imports and is expected to be in forefront in ocean and road freight forwarding industry.

Roadways has gained attraction in Thailand due to its superior road network, thus becoming the first preference for moving freight within the country with a vast presence of local freight forwarders coupled with trucking fleet operators. The government of Thailand’s emphasis on expanding and upgrading the railway network in the country with a focus on the double track railways has attracted close to THB 500 billion of fund allocation under the Thailand Transport Infrastructure Strategies 2022.  The government has laid special focus in ensuring that the countries land borders are seamlessly connected to the ASEAN network and the country has a good access to the Chinese and Indian market which will further help to strengthen the country’s trade relations. Additionally, the development of sea port infrastructure will support increasing cargo volumes throughout the large ports and free zones in the coming years with an improvement in port capacity and connectivity.

Analysts at Ken Research in their latest publication “Thailand Freight Forwarding Market Outlook to 2022 – By Freight Movement (Sea, Road, Air and Rail Freight); By Normal and Express Delivery; By International and Domestic Freight; By International Flow Corridors and By Third Party Logistics” believe that increasing the number of channel points, strengthening infrastructure connections, improving service quality in terms of training the personnel and promoting railways for freight transportation will have a positive impact on market.

Thailand freight forwarding market is expected to register a positive CAGR of 4.8% during the forecast period 2017-2022. The market is further expected to be driven by the growing demand due to picking up of the global markets including China, growing consumer preference for online shopping, upcoming infrastructure in the country & continuous investment by the government in development of logistics infrastructure and consistent economic growth.

Key Topics Covered in the Report:
Logistic Service Providers Thailand
Freight Forwarding Cost Thailand
Transport Infrastructure in Thailand
Road Freight Market Thailand
Freight Forwarding Services in Thailand
Freight Forwarding Services in Bangkok
Free Trade Agreements of Thailand
Freight Forwarders in Thailand
Shipping Fleet of Major Thailand Seaports
Cargo throughout Thailand Seaport
Recommendations Thailand Freight
Recommendations Thailand Transport Infrastructure

Key Segments Covered
By Freight Movement
·         Pipelines
·         Railways
·         Road
·         Sea
·         Air
·         Transportation Services and Postal services & communications

By Delivery:
·         Normal
·         Express

By Freight Forwarding
·         International
·         Domestic

By Flow Corridors
·         Asian Countries
·         NAFTA Countries
·         European Countries and Others

By Companies
·         International Companies
·         Domestic Companies

Key Target Audience
·         Shipping Companies
·         Freight Forwarders
·         Logistics Association
·         Express and E-Commerce Logistics Companies
·         Consulting service providers
·         Private Equity/ VCs/ Investment Banking Companies

Time Period Captured in the Report:
2012-2017 – Historical Period
2018-2022 – Future Forecast

Companies Covered:
·         Damco Thailand
·         DHL Thailand
·         Triple I
·         Kerry Logistics Thailand
·         NCL Logistics Thailand
·         Nippon Express Thailand
·         DB Shenker
·         WICE Logistics
·         SIAM Shipping
·         Agility
·         Bangkok Freight Forwarders
·         Royaltainer
·         Axium Shipping

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Ken Research
Ankur Gupta, Head Marketing & Communications
+91 9015378249