In
modern times the medical field is constantly innovating to provide solutions
for a variety of diseases. While there is no vaccine for parasitic diseases
there is medication available today that can help people tackle the problem.
Parasitic infections can usually be treated with anti parasitic drugs. Such
drugs are undergoing extensive research today.
Many
new projects are being explored around the world. Advances in science
especially in the field of parasite genomics and its attendant technology have
opened up possibilities for new drugs in common diseases like malaria.
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Many researchers
are taking steps in the direction of malaria eradication. Antifolate drugs in
malaria are experiencing resurgence with the development of Lapdap
(chlorproguanil-dapsone) nearing completion and an active programme devoted to
the Triazine WR99210. However, the progress of malaria eradication is
threatened by drug resistance and hence, medical research is also attempting to
control the transmission of parasitic diseases. Two recently conducted studies
characterize Plasmodium falciparum PKG inhibitors and Hexahydroquinolines as
anti malarial compounds that could block transmission and help mitigate the
risk of parasite escape via drug resistance.
·
The University of
California San Diego has recently launched a new center for anti-parasitic drug
discovery and development.
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Along with this
many contract research organizations (CROs) that provide support to
pharmaceutical, biotechnical and medical device industries in the form of
research services are also active in parasitic research. Laboratory Corporation
of America Holdings (Covance), IQVIA and Syneos Health are all American
clinical research organizations which are notable in this respect and are considered
the best global contract research organizations.
According
to the study “Parasitic
Diseases Global Clinical Trials H1 2018” suggests that agencies are
assisting in global efforts in this direction especially towards tackling
malaria. International organizations such as WHO have begun aiding drug
companies and related projects. They have been supported by economic agencies
who state that unhealthy countries are condemned to slow growth. Initiatives
such as Medicines for Malaria Venture are a result of such cooperation. A
global trend has also been noticed that CROs have begun coordinating with
government agencies and nonprofit organizations.
Renowned
companies like GlaxoSmithKline plc, which is the UK’s largest drug maker, and
Swiss Novartis AG are contributing to research funds that are global efforts
and aim to combat malaria led by the Bill and Melinda Gates Foundation. Such
research funds are receiving widespread support.
The
current global trend reveals that parasitic diseases are not only furthering
medical research but are raising awareness among people about just how lethal
common parasitic disease like malaria can be. Such diseases are being tackled
with medication but continuous and relentless efforts have begun to pay off,
visible by various recent discoveries made. Strong Individual drugs have now
been developed for malaria. These drugs are believed to be effective not only
because of their increased vigor but also because of their characteristic to
prevent further transmission of the disease. Even educational research
institutions have contributed along with CROs. The latter’s cooperation with
other agencies and global monetary funds raised in interest of public welfare
clearly indicate developments in parasitic disease treatment with malaria being
at its forefront.
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Ankur
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