According to the study, ‘HYPOTHYROIDISM GLOBAL CLINICAL TRIALS REVIEW, H1,
2018’, the
major organizations conducting clinical trials in the treatment of hypothyroidism
include IBSA
Institut Biochimique SA, Mylan NV, PRACS Institute, Ltd., Akrimax
Pharmaceuticals LLC, Vale Pharmaceuticals Ltd, Uni-Pharma SA, Teva
Pharmaceutical Industries Ltd, Takeda Pharmaceutical Co Ltd, Ipe LLC, Dompe
Farmaceutici SpA. Scientists from Rush University Medical Center have recently
gained new knowledge on hypothyroidism. This condition affects humungous
population alone in the United States. The study involved rats whose thyroid
gland was removed. The study aimed at knowing why circulating different levels
of T4 alone does not correct all the symptoms in all the patients. The study
revealed that the patients that had received T4 alone had higher cholesterol as
compared to the subjects that received combination of T4 and T3. These subjects
also showed signs of hypothyroidism in brain which could one of the possible explanations
of the ‘foggy brain’ symptom that is experienced by hypothyroid patients.
Hypothyroidism
is a situation when the body of an individual is not able to produce adequate
thyroid hormones. Thyroid is a gland that is present at the front of an
individual’s neck that releases hormones which allow regulation of usage of
energy. The thyroid is responsible for providing energy to all organs in a
person’s body. It regulates how the heart beats or how the digestive system
functions. If the thyroid does not produce adequate hormones then normal life
processes begin to slow down. For nearly a century, natural thyroid
preparations are used to treat hypothyroidism which contains thyroxine and triiodothyronine. The dosage of this
treatment was adjusted according to the severity of the condition. The standard
treatment involved using T4 supplements on a daily basis which later converted
to T3 within the body. However a small percentage of population affected by
this condition is not relieved of all the symptoms. The scientists suggest that
this could probably be due to the subjectivity as to how people feel. Many
people feel symptoms of this condition due to post menopause syndrome or
clinical depression.
A new study conducted on large population by the University
of Groningen in Netherland reveals that the people who consume thyroid
replacement hormone, Levothyroxine may have more co morbidities and lower
quality of life as compared to those who do not consume the hormone. The
presence of co morbidities was witnessed to have a more negative impact on the
quality of life of T4 users. Keeping in mind this research, scientists are
conducting research to improve the condition of hypothyroid along with working
to enhance the quality of life.
The condition of hypothyroidism is very common throughout the
world without a known 100 percent successful treatment. Companies and
institutions are pursuing clinical trials in order to achieve a successful
treatment and gain the first mover advantage. Considering this condition is
extremely common, the growth potential that lies in this industry is immense.
Companies shall need to realize this potential in order to tap the untapped
market.
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