According
to the study ‘OSTEOMYELITIS GLOBAL CLINICAL
TRIALS REVIEW, H1, 2018’, this infection is
usually treated with antibiotics given into veins or through surgery.
Osteomyelitis
is an infection of a bone caused by bacteria, mostly Staphylococcus aureus. It
is pretty rare and certain chronic conditions like diabetes tend to increase
the risk of osteomyelitis. It results in pain and redness around the affected
region apart from symptoms like fever, nausea and chills. The disease can
easily be diagnosed by X-ray, CT scan and blood tests. There are currently many
advances being made in surgical treatment and medicine which are incorporating
technology and research. The result of these advances in surgical treatment and
antibiotic therapy is opening doors for various treatment options of
osteomyelitis. The barriers to proper treatment are being studied in order to
better understand the ways to intrude them. This can be proven by the developments
that have taken place in osteomyelitis treatment such as the study carried out
by research teams. An Institut Pasteur-CNRS research team has characterized a
Staphylococcus aureus gene involved in virulence, bio film formation and
resistance to certain antibiotics.
Since
osteomyelitis is mainly an infection, it can easily flourish around open wounds
and recently treated areas around bones. New technologies for the prevention of
healthcare associated infections are increasingly being developed and marketed
to healthcare centers worldwide. This comes due to the realization of the fact
that while there is substantial promise in simulated test environments,
decreasing infections in the clinical setting has not been well established.
There are a number of factors that raise concern in this respect, the most
common ones being cross transmission in the hospital environment arising from
contamination of hospital surfaces, contamination of medical devices and hands
or clothes of medical personnel. Studies too show the alarming situation as
more than one-third of hospital acquired infections are caused by contamination
of medical workers’ hands. A patient admitted to a hospital room in which the
previous occupant had methicillin-resistant Staphylococcus aureus has a
significantly increased risk of acquiring the pathogens.
In
response to the crippling situation, there have been a number of developments
like the use of Adenosine triphosphate (ATP) levels and fluorescent markers to
monitor the microbial contamination levels. Manual cleaning remains an
important precursor step as gross organic soil must be removed from surfaces to
allow penetration of germicidal vapour/aerosol or radiation emitted from hydrogen
peroxide or UV light emitting devices. Several antimicrobial coatings are under
pre-clinical study for their potential application to surfaces in healthcare centers.
However, Coatings copper has been studied most extensively.
Antibiotics
are increasingly undergoing research to increase their effectiveness. Many
pharmaceutical companies are incorporating existing knowledge and expertise in
their experiments in an order to expand their scope. Osteomyelitis among other
ailments is providing opportunities to the pharmaceutical research sector to
tackle microbial attacks. There is growing awareness about prevention of
accelerating factors like hygiene and technologies like hand hygiene monitoring
systems and antimicrobial textiles among others are said to help change the
scenario.
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Ken
Research
Ankur
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+91-9015378249