Hypromellose acetate succinate (HPMCAS) is an enteric coating material, obtained from Shin‐Etsu chemical, whose acetyl and succinyl group contents are 8% and 15%, respectively. HPMCAS is commonly used in oral therapeutic formulations as a film coating for tablets or granules. It exhibits high solubility through solid dispersion. It is insoluble in gastric fluid but swell and dissolves rapidly in the upper intestine. It is used alone or in combination with soluble or insoluble binders in the preparation of granules with persistent drug-release properties such as controlled-release agents, film-forming agents, enteric coating agents, sustained-release agent, functional category, the release rate is pH-dependent and solubility enhancing agent.
According to the study, “Global Hypromellose Acetate Succinate Market 2019 by Manufacturers, Regions, Type, and Application, Forecast to 2024” the key companies operating in the global hypromellose acetate succinate market are Ashland Inc., Huzhou Zhanwang Pharmaceutical Co., Ltd., Shandong Head Co. Ltd., Shin-Etsu Chemical Co. Ltd., Zhejiang Haishen Chemical Co., Ltd., Shandong Yiteng New Material Co. Ltd., Lotte Chemical Corporation, The DowChemical Company, Celotech Chemical, Anhui Sunhere Pharmaceutical Excipients, Gemez Chemical, Hopetop Pharmaceutical, Hercules Tianpu, Yixing Hongbo Fine Chemical Co., Ltd.
Based on type, the hypromellose acetate succinate market is segmented into propylene glycol, ethylene glycol, and others. Based on product type, the market is segmented into primary antibody and secondary antibody. Based on the thermogravimetric analysis, the market is segmented into isothermal heating, ramp heating, and Brabender mixer.
Based on rheological characterization, the market is segmented into an oscillatory rheometer, capillary rheometer, hot-melt extrusion, viscoelastic properties, yellowness index, true density, high-performance liquid chromatography, x-ray powder diffraction, differential scanning calorimetry, scanning electron microscopy and x-ray powder diffraction. Based on the viscosity type, the market is segmented into high viscosity, middle viscosity, and low viscosity. Based on grade type, the market is segmented into L grade, H grade, and M grade. Based on the application, the market is segmented into solid dispersion, enteric film coating, and others. Solid dispersion is a technology that objectives to improve the bioavailability of poorly soluble active ingredients by enhancing their solubility. In addition, based on end-use, the market is segmented into the food industry, construction industry, pharmaceutical & cosmetics industry, and others.
The hypromellose acetate succinate market is driven by growth in pharmaceuticals and the healthcare industry, followed by a surge in raw material sources, high demand from low-fat foods, rapidly increasing demand for hypromellose acetate succinate, and growth in technological developments. However, growth in food regulations related to hypromellose acetate succinate and high cost associated with pharmaceutical-grade may impact the market. Moreover, the high demand for oral drug delivery in healthcare the industry is a key opportunity for the market.
Based on geography, the Asian-Pacific region holds a major share, followed by the European region in the hypromellose acetate succinate market owing to the increase in demand from food & beverages and pharmaceutical industry in the region. The North-American region is likely to witness a higher growth rate due to a rise in demand from paint & coating and mining applications over the forecast period. The worldwide market is projected to grow at a CAGR of approximately 10.4% over the next five years, will reach the US $47200 million in 2024, from the US $26100 million in 2019.
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