Top 3 US Pharmaceutical Companies and Their Strategies in US Acute Myeloid Leukemia Market

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US Acute Myeloid Leukemia Market is growing due to advancement in treatment approaches, increase healthcare costs and expenditure, growing investments in Research and Development, and a constant growth in population.

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• Pfizer Inc.- An American multinational company with the highest annual revenue of around 100 billion US$ in 2022 in the drug market. The company has made significant contributions to the US Acute Myeloid Leukemia Market through a sophisticated, robust, agile manufacturing infrastructure and investment in research and development.

• Brystol Myers Squibb- One of the largest American pharmaceutical companies which consistently ranks on the Fortune 500 list of the largest US corporations. The company’s mission is to discover, develop, and deliver innovative medicines that help patients as well as prevail over serious diseases.

• Novartis AG- The company with the fourth-largest revenue in the drug market which is focused to deliver high-value medicine that alleviate society’s greatest disease burdens through technology leadership in R&D and novel access approaches.
• The US Acute Myeloid Leukemia Market is expected to grow at CAGR of 10.5% in the forecast period 2022-2028.

The Acute Myeloid Leukemia Market of US is driving growth at an amazing level. This surge is a result of advancement in treatment approaches, increases healthcare costs and expenditure, growing investments in Research and Development, and a constant growth in population.

Various pharmaceutical companies are actively shaping this growing market with their strategies and innovations.

This article provides an in-depth look at major pharmaceutical companies with their strategies and innovations.

1.Pfizer Inc.

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Pfizer Inc. is an American multinational pharmaceutical company and headquartered at The Spiral in Manhattan, New York City. The company has made significant contributions to the US Acute Myeloid Leukemia Market through a sophisticated, robust, agile manufacturing infrastructure and investing in research and development.

The company employs more than 30,000 employees worldwide, have 35+ manufacturing sites, 300+ external suppliers, and have reached more than 180 countries. Pfizer tops the list of drug market by achieving a revenue of approx. 100 billion USD in 2022.

Pfizer has made significant contributions to the US acute Myeloid Leukemia Market. Some notable contributions are, in April 2017, the development and approval of a targeted therapy called “Rydapt”, which is an oral kinase inhibitor that targets multiple enzymes, including FLt3, which is often mutated in AML patients. The drug was approved by FDA in April 2017 for use in combination with Chemotherapy.

Furthermore, MYLOTARG is approved in combination with daunorubicin and cytarabine for the treatment of patients aged 15 and above with previously untreated, de novo, CD33-positive acute myeloid leukemia (AML), except Acute Promyelocytic Leukemia (APL).

The company’s purpose is “Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.

The company says that its purpose ensures that its patients remain at the center of all that they do. They live with their purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to their medicines.

Pfizer believes in growing partnerships with innovators to initiate forward great science and continually seek new partners that are actively researching bold scientific ideas. In December 2022, Pfizer announced its collaboration with Gero’s machine learning technology platform to discover potential therapeutic targets for fibrotic using large-scale human-based data.

Pfizer’s continuous clinical trials and collaboration with healthcare institutions and research organizations has majorly contributed in advancing Acute Myeloid Leukemia Market and the development of novel treatment strategies.

2.Bristol Myers Squibb

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The Bristol Myers Squibb Company, is an American multinational pharmaceutical company headquartered in Princeton, New Jersey. BMS is one of the world’s largest pharmaceutical companies and consistently ranks on the Fortune 500 list of the largest US corporations.

The company employs more than 34,000 across more than 86 locations worldwide. The company’s revenue in 2022 was approximately 46 bn USD.

Their mission is to discover, develop, and deliver innovative medicines that help patients as well as prevail over serious diseases. Bristol believes in the power of science to address some most challenging diseases of today's world.

Bristol Myers is majorly known for its contributions to oncology, and immunology and its involvement in Acute Myeloid Leukemia Market with its broader focus on cancer treatments.

The significant development of BMS can be noted from June 2021, Bristol Myers Squibb received approval from European Commission for Onureg, a Frontline oral maintenance therapy for adult patients with acute Myeloid Leukemia who achieved their first complete remission (CR) or CR with incomplete blood count recovery following intensive induction chemotherapy. Onureg is expected to increase sales and product revenue, thereby increasing the US Acute Myeloid Leukemia Market growth.

Furthermore, the strategic cooperation between Evotec and Bristol Myers Squibb has grown in order to create a pipeline for programs addressing more neurological illnesses. In order to find altering therapies for a variety of neurodegenerative disorders, the firms started working together in 2016. The eight-year extension is intended to strengthen the strategic partnership even more.

3.Novartis AG

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Novartis AG is a healthcare company that majorly focuses on the discovery, development, manufacture and marketing of prescription and generic pharmaceutical and eye care products. Novartis offers generic medicines and biosimilars through Sandoz. The company conducts its research through The Novartis Institute for Biomedical Research (NIBR).

Novartis is one of the largest pharmaceutical companies in the world and the fourth largest by revenue in 2022, which was approx. 50.500 billion USD.

The company is functioning in more than 150 locations with around 1,10,000 employees working worldwide.

Novartis's strategy as a focused medicines company is to deliver high-value medicine that alleviates society’s greatest disease burdens through technology leadership in R&D an novel access approaches.

Novartis contribution to Acute Myeloid Leukemia Market includes, FDA approval of Novartis Scemblix (asciminib), with novel mechanism of action for the treatment of Leukemia in October,2021.

Furthermore, through their open approach Novartis is focusing on new technologies to develop next generation therapeutics. Currently, Novartis is working with Orionis Bioscience to find new targets at a genome-wide scale.

By combining development and drug discovery with innovation, they aim to achieve tenuous targets and to launch novel small molecule therapy for Acute Myeloid Leukemia patients more quickly. Thus driving a steered growth for the US Acute Myeloid Leukemia Market.

Indonesia Car Rental Market, overview and genesis of the industry Outlook to 2027F : Ken Research

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What is the Size of Indonesia car rental Industry?

Indonesia Car Rental market is growing at a CAGR of ~% in 2017-2022 and is expected to reach USD  Bn by 2027F.

The Indonesia Car Rental Market is largely driven by expanding middle class, growing tourism sector, and the emergence of ride-hailing.

The expanding middle class and rising disposable income in the country is driving the demand for car rentals. As more individuals attain higher levels of income and financial stability, they seek convenient transportation options for various purposes, including business trips, family outings, and leisure activities. This increasing affluence translates into a higher propensity for individuals to rent vehicles, especially for short-term periods.

Furthermore, the emergence and development of ride-hailing services and shared mobility platforms have contributed to the growth of the car rental market. These platforms have gained immense popularity in Indonesia, providing on-demand transportation services to a large user base.

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Indonesia is a popular tourist destination, attracting millions of visitors each year. The growth in international and domestic tourism has increased the demand for rental cars as travelers prefer the convenience and flexibility of having their own transportation.

Rapid urbanization and improved infrastructure have made it easier for people to access car rental services, particularly in major cities like Jakarta, Bali, Surabaya, and Bandung.

Indonesia Car Rental Market by type of vechiles

• The Indonesia Car Rental market is segmented by type of vehicles into small cars/hatchbacks, Sedans, SUVs and others.
• The Small Cars/Hatchbacks are the dominant segment in the market in 2022.
• These vehicles are cost-effective, fuel-efficient, and well-suited for navigating congested urban areas. They are popular among both domestic and international travelers looking for affordable and practical transportation options. Additionally, small cars/hatchbacks generally offer better availability and a wider range of options compared to other segments.

Indonesia Car Rental MARKET by market structure

• The Indonesia Car Rental market is segmented by market structure into organized and unorganized market structure.
• Organized market structure is the dominant segment in the market in 2022.
• Organized car rental companies typically have established operations, professional services, standardized processes, and a wide range of vehicle options. They offer greater reliability, quality assurance, and customer support, making them preferred choices for both individual and corporate customers seeking a more structured and trustworthy car rental experience.

Indonesia Car Rental MARKET by ICE/EV

• The Indonesia Car Rental market is segmented by ICE/EV into
• ICE (Internal Combustion Engine) and
• Electric Vehicles.
• The internal Combustion engine segment in the dominant segment in the Indonesia Car rental market in 2022.
• This is because electric vehicles (EVs) are still relatively new and their infrastructure, such as charging stations, may not be as widespread or readily available in Indonesia compared to countries with more mature EV markets. However, it's important to note that the adoption of EVs is growing globally, and the dominance of segments may shift in the future.

Indonesia Car Rental MARKET by Mode of Booking

• The Indonesia Car Rental market is segmented by mode of booking into online and offline.
• Online booking dominates the Indonesia car rental market in terms of revenue in 2022 and is registers a significant growth in terms of revenue during the forecast period. The rise in the use of internet and mobile phone applications across the country is likely to enhance the use of online booking platforms.

Indonesia Car Rental MARKET by application

• The Indonesia Car Rental market is segmented by application into business and leisure.
• Leisure trips hold a significant market share in the Indonesia car rental market in 2022, due to the increasing number of tourist arrivals contributing to increasing the country’s GDP as well.

Indonesia Car Rental MARKET by Region

• The Indonesia Car Rental market is segmented by Region into Jakarta, Surabaya, Bali, Yogyakarta and Others.
• Jakarta hold the most dominant region in the Indonesia car rental market in 2022.
• Jakarta, as the capital city and a major economic hub, would be a dominant segment due to its large population, higher tourism activity, and business travel. Surabaya, Bali, and Yogyakarta are also popular tourist destinations. These regions also include popular tourist spots such as Bandung, Lombok, and Medan. The demand for car rentals in these areas is influenced by factors like tourism attractions, business activities, and transportation infrastructure, making them potential dominant segments in the market.

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Competition Scenario in Indonesia Car Rental Market

The competition scenario in the Indonesia car rental market is characterized by a mix of established car rental companies, regional players, and local operators. The market is relatively fragmented, with a wide range of options available to consumers. Established car rental companies and online aggregators dominate the organized segment, offering a diverse fleet of vehicles, competitive pricing, and convenient online booking platforms. These players often have nationwide or regional networks and cater to both individual and corporate customers.

However, the market also comprises numerous smaller, unorganized operators, especially in tourist destinations and local markets. These operators may offer more flexible pricing options but may have limitations in terms of fleet size, service quality, and consistency.

What is the Expected Future Outlook for the Overall Indonesia Car Rental Market?

The Indonesia Car Rental market was valued at USD ~billion in 2022 and is anticipated to reach USD ~billion by the end of 2027F, witnessing a CAGR of ~% during the forecast period 2022-2027F. The realistic growth scenario represents the most likely scenario as per current market conditions. This scenario assumes that there will be no overall impact on the market due to any potential COVID-19 waves in the future.

The Indonesia Car Rental market is driven by expanding middle class, growing tourism sector, and the emergence of ride-hailing. However, the market is also constantly being influenced by rapid development in technology, product innovation, and diversification in some countries.

For Instance, In June 2022, an exciting development took place as CARRO and PT Mitra Pinasthika MustikaTBK joined forces through a binding agreement. The collaboration involved a substantial investment of SGD 75 million (approximately USD 55.7 million) by CARRO, resulting in the acquisition of a 50% ownership stake in PT Mitra Pinasthika MustikaTBK. This strategic alliance marked a significant milestone in their partnership, setting the stage for future growth and cooperation in the market.

In May 2022, PT Blue Bird Tbk and PT AngkasaPura made an official announcement regarding their partnership. The collaboration aimed to offer convenient and comfortable transportation services for travelers from

Jenderal Ahmad Yani International Airport to various destinations in Semarang. This strategic alliance was in line with Blue Bird's mission to promote mobility as a service and support the transportation ecosystem of the airport. By joining forces, the two companies aimed to enhance the overall travel experience for passengers, ensuring seamless connectivity and efficient transportation solutions.

Furthermore, During March 2022, Minister of Tourism and Creative Economy, Sandiaga Uno, engaged in a significant meeting with 18 foreign investors. The purpose of the meeting was to present sustainable tourism projects amounting to USD 1.5 billion. These projects were aimed at bolstering the tourism industry in Indonesia and were expected to contribute to approximately 20% of the sector's growth. Moreover, the investments were projected to contribute to a 5% expansion in the overall national economy for the year 2022.

In conclusion, the future outlook of the car rental market in Indonesia appears promising. Factors such as the expanding middle class, growing tourism sector, and the emergence of ride-hailing services are likely to drive demand. However, increasing competition may lead to price wars and improved services. The market may also witness a shift towards electric vehicles, necessitating infrastructure development. Furthermore, technology integration and government regulations will play crucial roles in shaping the industry's future.

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Indonesia Car Rental Market

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India Water Purifier Market, Share and Industry Report, Outlook to FY2025: Ken Research

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How is India Water Purifier Market is Positioned?

India Water Purifier Market comprises of both organized and unorganized players. The unorganized players contributes majority of the share in the volume whereas organized players contributes for majority of the revenues. Currently the penetration for water purifier is quite low in India especially in the rural areas. Consumers consider it as a luxury product rather than a necessity product. However, the perception has started to change in the recent years due to the marketing initiative of the companies. Water quality is deteriorating in many places due to which the consumers over there are adapting to the usage of water purifiers. The companies are focusing on the technological developments in order to increase their market presence.

The water purifier market witnessed a growth of CAGR ~% during FY’2017-FY’2022 in terms of volume. The revenue CAGR during the period was ~%. The market is witnessing strong growth. New companies entered in the market which brought down the average selling prices however the decline stagnated later. This will help the organized players in competing with the unorganized players. The players are focusing on increasing their retail presence and service partners for increasing their reach and after sales service. The unorganized players compete on the basis low prices and low AMCs for maintain their position in the market.

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India Water Purifier Market Segmentation

By Market Structure: The water purifier market in India is dominated by organized market in terms of revenue. However in terms of volume the unorganized market has more revenues.

By Sales Channel: The major sales channels used in market are Offline Retail Channel, Direct Sales Channel and Online Channel. Offline retail channel contributed majority of the revenues.

By Technology: RO Water Purifiers contributed the most of the revenues in the market followed by UV Water Purifiers and Gravity Water Purifiers respectively.  Gravity was leader in terms of Volume Sales.

By End Users: Residential users contributed the majority of the revenues in the market.

By Region:  West was the biggest market. It is followed by North, South and East regions.

What are the Major Issues and Challenges in the Water Purifier Market in India?

Low Awareness: Consumers mostly consider water purifiers as a luxury product rather than a necessity product as they are not aware about the different type of diseases caused by drinking poor quality water.

Preference of Alternatives: A large part of population still uses traditional method such as filtering with cloth and boiling for purifying water. Another major portion of population relies on Bottled Water Jars for their drinking water needs.

High Maintenance Charges: Consumers feel that the company charges extra premium from them on service of water purifiers. Therefore the customers do not follow the scheduled service periods or uses local service providers.

Lack of Proper Distribution Channel: Water purifiers have low penetration especially in the rural areas. There is lack of retail outlets in the rural areas. These areas also do not get proper after sales service. This has motivated the customers.

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What are the Major Government Rules and Regulations?

The Bureau of Standards India has issued IS 10500:2012 which specifies the norms to be followed for drinking water in India. It mentions the permissible residual limit and other quality norms.

The Bureau has also issued IS 16240: 2015 for Reverse Osmosis Water Purifiers, IS 14724: 1999 for Ultra Violet Disinfection Water Purifiers and IS 7402:2011 for Ceramic Candle specifications.

In 2021, the National Green Tribunal ordered the Ministry of Environment, Forest and Climate Change to ban usage of RO water purifiers in areas having TDS level below 500 milligrams per liter.

Competitive Scenario in the India Water Purifier Market

The competition in the India water purifier market is slightly concentrated as the top three players holds ~% market on the basis of retail revenues as of FY’2022. The unorganized market had a retail revenue contribution of ~% in the year. The companies compete on the parameters such as Brand Image, Price, Serviceability, AMCs, Technological Advancements and others. The Major players present in the market are Eureka Forbes Ltd, Kent RO Systems Ltd, Livpure (Hindustan Unilever) and others.

India Water Purifier Market Future Outlook and Projections

The water purifier market of India is expected to witness decent double digit growth in terms of volume in the future period. The revenue growth will decline a little. This will happen as the organized companies will focus more on profitability. The unorganized market will focus on competing on low prices, low AMCs and personalized services.  The major penetration will happen in rural areas. As these areas are electrified and their income level is increasing, the consumers from here will facilitate the next wave of demand. The companies need to strengthen their retail presence and service centers in these areas in order to encash this opportunity. The market is expected to witness a CAGR of ~% during FY’2022-FY’2027F in terms of revenue and ~% in terms of volume.

For More Insights On Market Intelligence, Refer to the link below: –

India Water Purifier Market

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